Journal: Psychoneuroendocrinology
Article Title: Adipokines in depressed women with and without adverse childhood experiences.
doi: 10.1016/j.psyneuen.2024.107026
Figure Lengend Snippet: Fig. 1. Average adipokine levels by group measured in serum by ELISA (a) Adiponectin: No group effects. (b) Leptin: Levels showed a main effect of MDD. (c) Adiponectin-to-leptin ratio: Main effect of ACE, however, the ratio was decreased in all clinical groups compared to HC (d) RBP4 (dilution 1:100,000): An ACE × MDD interaction effect indicated that compared to healthy controls, RBP4 levels were decreased for ACE-only and MDD-only individuals. Interestingly, RBP4 discriminated between individuals who did (ACE+MDD) or did not (ACE-only) develop MDD after ACE, with lower levels for individuals who were not affected by MDD despite of ACE experience. Error bars represent standard deviation. Abbreviations: HC = healthy controls, ACE = adverse childhood events, MDD = major depressive disorder, RPB4 = retinol binding protein 4.
Article Snippet: LEP ELISA KitTM (Human), OKBB00206 and ADIPOQ ELISA KitTM (Human), OKBB00291, Aviva Systems Biology, Corp, CA, USA, respectively) and BioOceanTM Human RBP4 ELISA Kit (EK1147, Bio-Ocean LLC, MN, USA) were used according to the manufacturer’s instructions.
Techniques: Enzyme-linked Immunosorbent Assay, Standard Deviation, Binding Assay